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Aripiprazole and Autism

Aripiprazole is a type of atypical antipsychotic medication sold under the brand names Abilify and Aripiprex.

It works by changing the activity of dopamine and other neurotransmitters in the brain and is used to treat the symptoms of schizophrenia, bipolar disorder and depression.

It is sometimes used to treat problem behaviours in people on the autism spectrum, including hyperactivity, aggression, and restricted, repetitive patterns of behaviour, interests, or activities.

Related Glossaries

Aripiprazole

Related Publications

Blankenship K. et al. (2010) Aripiprazole for irritability associated with autistic disorder in children and adolescents aged 6-17 years. Pediatric Health. 4(4), Read Abstract (New Window) Read Full (New Window)
Ching H., Pringsheim T. (2012) Aripiprazole for autism spectrum disorders (ASD). Cochrane Database of Systematic Reviews. Read Abstract (New Window) Read Full (New Window)
Curran M. (2011) Aripiprazole: in the treatment of irritability associated with autistic disorder in pediatric patients. Pediatric Drugs. 13(3), Read Abstract (New Window)
Deb S. et al. (2014) The effectiveness of aripiprazole in the management of problem behaviour in people with intellectual disabilities, developmental disabilities and/or autistic spectrum disorder: A systematic review. Research in Developmental Disabilities. 35(3), Read Abstract (New Window)
Erickson C. A. et al. (2010) Aripiprazole in autism spectrum disorders and fragile X syndrome. Neurotherapeutics. 7(3), Read Abstract (New Window)
Farmer C. A., Aman M. G. (2011) Aripiprazole for the treatment of irritability associated with autism. Expert Opinion on Pharmacotherapy. 12(4), Read Abstract (New Window)
Findling R. L. et al. (2014) A randomized controlled trial investigating the safety and efficacy of aripiprazole in the long-term maintenance treatment of pediatric patients with irritability associated with autistic disorder. Journal of Clinical Psychiatry. 75(1), Read Abstract (New Window)
Kim Y. et al. (2010) Retrospective case series of aripiprazole augmentation in pervasive developmental disorders. Psychiatry Investigations. 7(3), Read Full (New Window)
Marcus R. N. et al. (2009) A placebo-controlled, fixed-dose study of aripiprazole in children and adolescents with irritability associated with autistic disorder. Journal of the American Academy of Child and Adolescent Psychiatry. 48(11), Read Abstract (New Window)
Marcus R. N. et al. (2011) Aripiprazole in the treatment of irritability in pediatric patients (aged 6-17 years) with autistic disorder: results from a 52-week, open-label study. Journal of Child and Adolescent Psychopharmacology. 21(3), Read Abstract (New Window)

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Updated: 18 Jun 2018

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