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Folate receptor autoimmunity and cerebral folate deficiency in low-functioning autism with neurological deficits.
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- Authors
- V.T. Ramaekers, N. Blau, J.M. Sequeira, M.C. Nassogne, E.V. Quadros
- Title
- Folate receptor autoimmunity and cerebral folate deficiency in low-functioning autism with neurological deficits.
- Journal
- Neuropediatrics
- Year
- 2007
- Volume
- 38
- Issue
- 6
- Page(s)
- pp 276-281
- Abstract Link
- Read Abstract (New Window)
- Publication Format
- Journal Article
- Efficacy Study/Review
- Yes
- Scientific Validity
- Peer-Reviewed
- Comments
- This was primarily a study of serum folate, cerebrospinal fluid (CSF) 5-methyltetrahydrofolate (5MTHF), and serum FR autoantibodies of the blocking type to determine the significance of folate receptor (FR) autoantibodies with respect to folate transport across the blood-CSF barrier in patients with early-onset low-functioning autism. However it also reported on clinical improvements, which were positive.
- Keywords
- Autism, Biomedical, Dietary Supplements, Folinic Acid, Intervention, Low Functioning / Severe, Oral / By Mouth, Rett Syndrome, Vitamin B-9, Vitamins
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