Aripiprazole and Autism
Ranking:
Studies and Trials
This section provides details of scientific studies into the effectiveness of aripiprazole for people on the autism spectrum which have been published in English-language, peer-reviewed journals.
If you know of any other publications we should list on this page please email info@informationautism.org
Please note that we are unable to supply publications unless we are listed as the publisher. However, if you are a UK resident you may be able to obtain them from your local public library, your college library or direct from the publisher.
Related Studies and Trials
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Aman M. G.
et al.
(2009)
Medication and parent training in children with pervasive developmental disorders and serious behavior problems: Results from a randomized clinical trial.
Journal of the American Academy of Child and Adolescent Psychiatry.
48(12),
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Aman M. G.
et al.
(2010)
Line-item analysis of the Aberrant Behavior Checklist: results from two studies of aripiprazole in the treatment of irritability associated with autistic disorder.
Journal of Child and Adolescent Psychopharmacology.
20(5),
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Basgul S. S. (2014)
Aripiprazole use in children and adolescents: A public hospital child psychiatry outpatient department’s experience.
Bulletin of Clinical Psychopharmacology.
24(1),
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Erickson C. A.
et al.
(2011)
A prospective open-label study of aripiprazole in fragile X syndrome.
Psychopharmacology (Berl).
216(1),
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Findling R. L.
et al.
(2014)
A randomized controlled trial investigating the safety and efficacy of aripiprazole in the long-term maintenance treatment of pediatric patients with irritability associated with autistic disorder.
Journal of Clinical Psychiatry.
75(1),
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Fung L. K.
et al.
(2012)
A retrospective review of the effectiveness of aripiprazole in the treatment of sensory abnormalities in autism.
Journal of Child and Adolescent Psychopharmacology.
22(3),
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Ghanizadeh A., Sahraeizadeh A., Berk M. (2014)
A head-to-head comparison of aripiprazole and risperidone for safety and treating autistic disorders, a randomized double blind clinical trial.
Child Psychiatry and Human Development.
45(2),
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Gibson A. P.
et al.
(2007)
Effectiveness and tolerability of aripiprazole in child and adolescent inpatients: a retrospective evaluation.
International Clinical Psychopharmacology.
22(2),
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Hellings J. A.
et al.
(2011)
Long-term aripiprazole in youth with developmental disabilities including autism.
Journal of Mental Health Research in Intellectual Disabilities.
4(1),
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Huang S., Tsai S., Yang H. (2010)
Aripiprazole improves social interaction in Taiwanese children with pervasive developmental disorder.
Chang Gung Medical Journal.
33(2),
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Ichikawa H.
et al.
Aripiprazole in the treatment of irritability in children and adolescents with autism spectrum disorder in Japan: A randomized, double-blind, placebo-controlled study.
Child Psychiatry and Human Development.
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Ishitobi M.
et al.
(2012)
Switching to aripiprazole in subjects with pervasive developmental disorders showing tolerability issues with risperidone.
Progress in Neuro-Psychopharmacology and Biological Psychiatry.
37(1),
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Ishitobi M.
et al.
(2013)
Effectiveness and tolerability of switching to aripiprazole from risperidone in subjects with autism spectrum disorders: a prospective open-label study.
Clinical Neuropharmacology.
36(5),
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Jordan I.
et al.
(2012)
Aripiprazole in the treatment of challenging behaviour in adults with autism spectrum disorder.
Psychopharmacology (Berl).
223(3),
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Kim Y.
et al.
(2010)
Retrospective case series of aripiprazole augmentation in pervasive developmental disorders.
Psychiatry Investigations.
7(3),
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Lamberti M.
et al.
(2016)
Head-to-head comparison of aripiprazole and risperidone in the treatment of ADHD symptoms in children with autistic spectrum disorder and ADHD: A pilot, open-label, randomized controlled study.
Pediatric Drugs.
18(4),
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Maloney A., Mick E., Frazier J. (2014)
Aripiprazole decreases irritability in 12 out of 14 youth with autism spectrum disorders.
Journal of Child and Adolescent Psychopharmacology.
24(6),
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Mankoski R.
et al.
(2013)
Aripiprazole treatment of irritability associated with autistic disorder and the relationship between prior antipsychotic exposure, adverse events, and weight change.
Journal of Child and Adolescent Psychopharmacology.
23(8),
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Marcus R. N.
et al.
(2009)
A placebo-controlled, fixed-dose study of aripiprazole in children and adolescents with irritability associated with autistic disorder.
Journal of the American Academy of Child and Adolescent Psychiatry.
48(11),
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Marcus R. N.
et al.
(2011)
Aripiprazole in the treatment of irritability in pediatric patients (aged 6-17 years) with autistic disorder: results from a 52-week, open-label study.
Journal of Child and Adolescent Psychopharmacology.
21(3),
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Marcus R. N.
et al.
(2011)
Safety and tolerability of aripiprazole for irritability in pediatric patients with autistic disorder: a 52-week, open-label, multicenter study.
Journal of Clinical Psychiatry.
72(9),
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Masi G.
et al.
(2009)
Aripiprazole monotherapy in children and young adolescents with pervasive developmental disorders: a retrospective study.
CNS Drugs.
23(6),
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Owen R.
et al.
(2009)
Aripiprazole in the treatment of irritability in children and adolescents with autistic disorder.
Pediatrics.
124(6),
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Robb A. S.
et al.
(2011)
Safety and tolerability of aripiprazole in the treatment of irritability associated with autistic disorder in pediatric subjects (6-17 years old):results from a pooled analysis of 2 studies.
Primary Care Companion to CNS Disorders.
13(1),
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Rugino T. A., Janvier Y. (2005)
Aripiprazole in children and adolescents: clinical experience.
20(7),
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Scahill L.
et al.
(2012)
Effects of risperidone and parent training on adaptive functioning in children with pervasive developmental disorders and serious behavioral problems.
Journal of the American Academy of Child and Adolescent Psychiatry.
51(2),
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Stigler K. A., Posey D. J., McDougle C. J. (2004)
Case report: aripiprazole for maladaptive behavior in pervasive developmental disorder.
Journal of Child and Adolescent Psychopharmacology.
14(3),
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Stigler K. A.
et al.
(2009)
Aripiprazole in pervasive developmental disorder not otherwise specified and Asperger's disorder: a 14-week, prospective, open-label study.
Journal of Child and Adolescent Psychopharmacology.
19(3),
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Valicenti-McDermott M. R., Demb H. D. (2006)
Clinical effects and adverse reactions of off-label use of aripiprazole in children and adolescents with developmental disabilities.
Journal of Child and Adolescent Psychopharmacology.
16(5),
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Varni J. W.
et al.
(2012)
Effect of aripiprazole 2 to 15 mg/d on health-related quality of life in the treatment of irritability associated with autistic disorder in children: A post hoc analysis of two controlled trials.
Clinical Therapeutics.
34(4),
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- Updated
- 17 Jun 2022
- Last Review
- 01 Jul 2018
- Next Review
- 01 Mar 2024